In this article, we will get acquainted with monopropylene glycol in veterinary medicine.Monopropylene glycol is a free-flowing fluid that is ideal for postpartum cows.It can be mixed with hyphae and molasses to provide an initial tank for cows.MPG can be used for both the prevention and treatment of ketosis.He also used MPG to improve calving in cows that give birth in poor conditions.Monopropylene glycol is a synthetic liquid substance that absorbs water. It is also used to make polyester compounds and as a base for impregnation solutions.Monopropylene glycol is used as an antifreeze in the chemical, food and pharmaceutical industries. Used to absorb excess water and retain moisture in some medicines, cosmetics or food products. It is a solvent for food colors and flavors and in the paint and plastics industries. It is also used to create artificial smoke or fog, which is used in firefighting exercises and theatrical productions. At room temperature the liquid is clear, colorless and slightly syrupy. It may be in the form of vapor in the air and is practically odorless.
In veterinary medicine, monopropylene glycol is used as a moisturizer in pet food with soft moisture, which helps to retain water and gives these products a unique texture and taste. It is generally safe for use in human and animal foods (GRAS) this is a Applications of monopropylene glycol.
Monopropylene glycol (MPG) reduces the molar ratio of acetate to propionate in ruminal volatile fatty acids (VFAs) in lactating cows because part of it is metabolized to propionate in the rumen. The remaining monopropylene glycol is unchanged, absorbed directly from the rumen and enters gluconeogenesis via pyruvate.Oral administration after soaking for 30 minutes increases insulin by 200-400%, which indicates that it is absorbed very quickly. It also raises plasma glucose, although the response is limited, probably due to a large increase in insulin. Reduces plasma concentrations of non-esterified fatty acids (NEFA) and beta-hydroxybutyrate (BHB), especially in relatively lactating cows with relatively high levels of monopropylene glycol. It reduces the amount of triacylglycerol (TG) in the liver and the concentration of ketone bodies in milk and therefore has anti-ketogenic properties. Factors such as the metabolic status of the animals, the time of blood sampling in relation to the feeding time of monopropylene glycol, the supplementation method and its dose affect the response rate in the blood parameters. In general, this substance has no statistically significant effect on milk production.But for cows in early lactation it tends to increase milk production and decrease milk fat percentage, while milk protein percentage is unchanged. Because it tastes good, it may reduce feed intake if not thoroughly mixed or soaked with other ingredients. Monopropylene glycol may improve reproductive performance, but more studies are needed to confirm this. Liver TG concentrations and milk fat content indicate that this substance increases the energy balance of cows in early lactation.
Studies show that on average about 30% of cows, like UK cows, are at risk for ketosis, most of them have latent ketosis and no obvious symptoms.For several reasons, cows experiencing some degree of ketosis are an embedded problem in dairy farms.This is a metabolic condition, meaning that the energy required in early lactation does not match the energy supplied by the feed.Body fat is mobilized as a natural process to compensate for the lack of energy. If the liver becomes too much motile fat needed to process the liver, the cow will develop ketosis.Cows with ketosis have lower performance, poorer fertility, and a wider range of other problems, including having a difficult delivery, preserved placenta, developing milk fever, displaced abortion, and being more likely to develop mastitis. To beNRG Liquid Energy is a high-energy, flavorful liquid supplement. Providing NRG to high-risk cows prevents ketosis only by providing the available fast energy to reduce the energy gap responsible for ketosis.NRG contains monopropylene glycol and glycerol, this formula allows more food to be fed, so in fact cows receive 1.75 times more energy than direct propylene glycol.Not all cows need NRG; cows that are most likely to be at risk for ketosis should use this substance.Although the drug is not authorized in veterinary medicine, NRG can be used in cases of ketosis to support bovine energy levels and direct TCA / lipid cycling. In such cases, give the cow 250 ml twice a day for 3 days.